β-Arbutin
β-Arbutin
β-Arbutin
CAS NO.:
497-76-7
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Product Introduction
ParameterDetails
Chemical Name4-Hydroxyphenyl-β-D-glucopyranoside
CAS Number497-76-7
Molecular FormulaC₁₂H₁₆O₇
Molecular Weight272.25 g/mol
Physical AppearanceWhite needle-like crystals or powder
SolubilitySoluble in hot water, methanol, ethanol; Insoluble in ether, chloroform
Primary SourceLeaves of Arctostaphylos uva-ursi (bearberry), also found in blueberries, cranberries
Core ApplicationSkin-lightening ingredient in cosmetics (whitening, freckle-reducing)
Whitening MechanismInhibits tyrosinase activity to block melanin synthesis; accelerates melanin decomposition and excretion
Safety Concentration Limit (EU SCCS, 2023)Max 7% in facial creams; Hydroquinone content should be kept at unavoidable trace levels
Formulation RequirementspH value ≥ 6.0; Avoid high temperature and UV exposure; Add antioxidants appropriately
AdvantagesCost-effective; Efficient skin-lightening effect without affecting skin cell proliferation
Potential DrawbacksPhotosensitive; May decompose into hydroquinone (a potential skin irritant) under certain conditions
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